Vytrus presents during the 30th IFSCC Congress

Vytrus Biotech CSO and Co-Founder PhD Oscar Expósito, gave a presentation during the 30th IFSCC Congress, celebrated in Munich the past 18-21 of September.  The congress is organized by the International Federation of Societies of Cosmetic Chemists (a worldwide federation dedicated to international cooperation in cosmetic science and Technology) and gathers the most important actors of the industry, with presentations that highlight the latest innovation and developments in the field. This year, under the tittle “Cosmetics: Science for Beauty and Lifestyle”, the conferences had a special focus on what modern society wants in terms of beauty and lifestyle.

Speaking at an IFSCC congress is not easy; for instance, Vytrus’ paper was one of the few selected, out of more than 600 candidates. The presentation took place on Thursday 20, during the morning session: “Shielding the Skin” in the main Auditorium, just after the keynote lecture

Titled “Microbiome Quorum Sensing modulation – A Genuine Mechanism of Action to Rebalance the Skin Microbiota Dysbiosis from a New Paradigm: Shoot the Message not the Messenger”, the presentation introduced Vytrus latest active ingredient QUORA NONI, which has just won the Cosmetorium Award 2018, and was one of the 10 finalists in the In Cosmetics Innovation Zone Awards, last spring.

QUORA NONI is a concentrated metabolome of totipotent cells from the Noni plant, rich in anti-quorum sensing molecules (Anti-Quormones) specially designed for “dermohacking”: to act synergistically against Quorum Sensing mediated microbial dysbiosis while perfecting the skin appearance.

The active offers a new mechanism of action to treat the microbiome dysbiosis that creates acne and other skin conditions. Microbes can talk to each other through a communication system called Quorum Sensing, that uses Quormones (communication signals). This bacteria communication is behind the health of our skin microbiome, and it is responsible of the formation of biofilms and virulence, with an imbalance in the microbe population.

QUORA NONI works as an anti-Quorum Sensing, blocking this communication signals to avoid the formation of biofilms and development of bacterial virulence, without killing or threatening the microbiome.  Because it doesn’t contain antibiotics, it avoids the potential resistance that microbes can develop, and also, it is bacteriostatic, maintaining the microbiome balance. In particular, its inhibition of the Gene Lux-S expression, responsible for the synthesis of Quormones, is a first time claimed mechanism of action, never described before.